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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride

CAS: 115473-15-9

Molecular Formula: C7H10ClNOS

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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL - Names and Identifiers

Name 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride
Synonyms Pragrael intermediate
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one HCL
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL
5,6,7,7a-Tetrahydro-thieno[3,2-c]pyridinone Hydrochloride
5,6,7,7a-Tetrahydro-4H-thieno[3,2-c] 2-pyridone hydrochloride
5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one hydrochloride
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-onehydrochloride
2-Oxo-2,4,5,6,7,7a-Hexahydro Thieno[3,2-c]pyridine Hydrochloride
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride
5,6,7,7a-Tetrahydro-thieno[3,2-c]pyridin-2(4H)-one Hydrochloride
2-oxo-2,4,5,6,7,7a-hexahydrothieno [3,2-c] pyridine. Hydrochloride
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride prasugrel intermediate I
CAS 115473-15-9
EINECS 601-365-4
InChI InChI=1/C7H9NOS.ClH/c9-7-3-5-4-8-2-1-6(5)10-7;/h3,6,8H,1-2,4H2;1H

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL - Physico-chemical Properties

Molecular FormulaC7H10ClNOS
Molar Mass191.68
Melting Point2100C (dec)
Boling Point364.3℃ at 760 mmHg
Solubility DMSO, Methanol, Water
AppearanceCream solid
ColorLight Tan
Storage ConditionInert atmosphere,Store in freezer, under -20°C
MDLMFCD11111130

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29349990
Hazard ClassIRRITANT

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL - Reference Information

prasugrel intermediate prasugrel is a thienopyridine antiplatelet drug developed by Eli Lilly and Japanese drugmaker First Pharmaceutical Sankyo (Daiichi Sankyo). It is a prodrug that forms active molecules after being metabolized by cytochrome P450 in the liver, which binds to platelet P2Y12 receptors to exert anti-platelet aggregation activity. Clinical studies have proved that the 60 mg dose has a better anticoagulant effect than the 300 mg standard dose of clopidogrel and the 600 mg increased dose, which can reduce the overall risk of heart attack, stroke, and death due to heart disease by 20%, and It has quick effect, good curative effect, good drug resistance and bioavailability, and low toxicity. Prasugrel also has stronger performance than clopidogrel in interventional surgery for stable angina and acute coronary syndrome, but the stronger the antiplatelet effect, the more likely it is to cause bleeding. The key question now is how to identify patients at high risk of thrombosis in clinical practice and how to identify people at high risk of bleeding, so that prasugrel and clopidogrel can be used differently in the two high-risk groups, which can reduce coronary thrombosis and avoid major bleeding. On December 18, 2008, prasugrel received its first important international recognition, and the European Medical Products Committee (CHMP) of the European Medicines Agency recommended the approval of the drug. The permission of the European Commission was passed in late February 2009. In Europe, it is sold under the trade name Efient for the treatment of acute coronary syndrome. The working principle of prasugrel is to inhibit platelet activation and concurrent aggregation by blocking P2Y12 adenosine diphosphate receptors on the platelet surface. Antiplatelet drugs are used to prevent platelets from gathering or sticking together. If platelets accumulate, they can cause artery blockage and may cause heart disease or stroke. On July 10, 2009, the U.S. Food and Drug Administration approved prasugrel tablets for patients undergoing angioplasty to reduce the risk of thrombosis. In April 2010, it was approved in Canada for the treatment of acute coronary syndrome. Prasugrel's label contains framed warnings to remind doctors that the drug may cause obvious and sometimes fatal bleeding. This product should not be used for the following patients: current pathological bleeding; a history of transient ischemic attack or stroke; or emergency surgery, including coronary artery bypass surgery.
Last Update：2024-04-09 21:04:16
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL
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Nantong Reform Petro-Chemical CO., LTD.
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Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Request for quotation
CAS: 115473-15-9
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Product Name: Prasugrel Impurity 25 Hydrochloride Request for quotation
CAS: 115473-15-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Request for quotation
CAS: 115473-15-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple Specifications
Product Name: 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Visit Supplier Webpage Request for quotation
CAS: 115473-15-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Hangzhou Verychem Science And Technology Co.Ltd
Product Name: Thieno[3,2-c]pyridin-2(4H)-one, 5,6,7,7a-tetrahydro-, hydrochloride Request for quotation
CAS: 115473-15-9
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302 Click to send a QQ message
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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one HCL
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